Frontotemporal Dementia

DEFINITION

According to Dr Jonathan Rohrer & Dr Jason Warren from the Dementia Research Centre of the University College London, Institute of Neurology, "FTD is a group of conditions caused by loss of cells mainly in the frontal and temporal lobes of the brain. The main symptoms are a progressive change in personality and behaviour or progressive deterioriation in language abilities." Please find more information on rare dementia support's website.

GUIDELINES RELEVANT FOR FTD

  • n.a.

CONSENSUS PAPERS

  • Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. Brain. 2011 Sep;134(Pt 9):2456-77.
  • Classification of primary progressive aphasia and its variants. Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, Ogar JM, Rohrer JD, Black S, Boeve BF, Manes F, Dronkers NF, Vandenberghe R, Rascovsky K, Patterson K, Miller BL, Knopman DS, Hodges JR, Mesulam MM, Grossman M. Neurology. 2011 Mar 15;76(11):1006-14.

DIAGNOSTIC ALGORITHMS

  • n.a.

EVIDENCE

  • None

REGISTRIES

  • Currently none – North American registry being set up at present

SCALES

NETWORKS AND STUDY GROUPS

PATIENT ORGANISATIONS

Textversion ausgeblendet

FTD-Frontotemporal Dementia RESOURCES

Guidelines relevant for FTD

  • n.a.

Consensus papers

  • Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. Brain. 2011 Sep;134(Pt 9):2456-77.
  • Classification of primary progressive aphasia and its variants. Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, Ogar JM, Rohrer JD, Black S, Boeve BF, Manes F, Dronkers NF, Vandenberghe R, Rascovsky K, Patterson K, Miller BL, Knopman DS, Hodges JR, Mesulam MM, Grossman M. Neurology. 2011 Mar 15;76(11):1006-14.

Diagnostic algorithms

  • n.a.

Evidence

  • None

Registries

  • Currently none – North American registry being set up at present

Scales

  • Frontotemporal dementia Rating Scale (FRS): for download from http://www.ftdrg.org/ace-r-download/frontotemporal-dementia-rating-scale-frs-download/

Networks and study groups

  • GENFI (Europe/Canada): genfi.org.uk
  • ARTFL (USA): https://www.rarediseasesnetwork.org/cms/ARTFL
  • LEFFTDS (USA): https://www.nia.nih.gov/alzheimers/clinical-trials/longitudinal-evaluation-familial-frontotemporal-dementia-lefftds

Advocacy and support groups

  • FTD support group (UK): https://www.ucl.ac.uk/drc/ftdsupport
  • Familial FTD support group (UK): https://www.ucl.ac.uk/drc/support-groups/fFTD-support-group
  • AFTD (US): http://www.theaftd.org
  • Australian AFTD (Australia): http://www.theaftd.org.au