Studies and Trials – Atypical Parkinsonian Syndromes

Ongoing

List of all Trials and Studies to which ERN-RND expert centers contribute
Type of studyAcronymTitleNCT IDOther study IDs
Clinical trialCYPRESS Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Multiple System Atrophy NCT05696717
Clinical trialLIGHTHOUSE A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating ScaleNCT05418673
Clinical trialA Study to Test the Safety and Tolerability of Long-term UCB0107 Administration in Study Participants with Progressive Supranuclear PalsyNCT04658199
Clinical trialA phase IIb, randomized, double-blind, placebo-controlled, multicenter, 52-week trial to evaluate the efficacy and safety of intravenous prasinezumab in patient with early Parkinson diseaseNCT04777331
Clinical trialA Randomized, Double-blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous TAK-341 in Subjects with Multiple System AtrophyNCT05526391
Clinical trialMASCOTA Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)NCT06706622
Clinical trialTOPAS-MSAA Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy (MSA): A Safety and Efficacy StudyNCT06568237
Clinical trialA Multicenter, Randomized, Active-controlled, Double-blind, Double-dummy, Parallel Group Study of the Efficacy, Safety, and Tolerability of Continuous SC ND0612 Infusion vs. Oral IR-LD/CD in Subjects With PD Experiencing Motor FluctuationsNCT04006210
Clinical trialA Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in Subjects With Parkinson’s Disease With a Pathogenic Variant in the Glucocerebrosidase (GBA1) GeneNCT05819359
Clinical trialHORIZONStudy to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System AtrophyNCT04165486
Clinical trialPROSPERA Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)NCT06355531FNP223-CT-2301
Observational studyROPADRostock International Parkinson's Disease StudyNCT03866603
Observational studyPPMIParkinson’s Progression Markers InitiativeNCT04477785
Observational studyELEGANCELong-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's DiseaseNCT05043103
Observational study PINK1/PRKN Project(not registered)