Virtual Consultation

Clinical Patient Management System (CPMS)

The Clinical Patient Management System (CPMS) is a secure web-based application to support European Reference Networks in the diagnosis and treatment of rare or low prevalence complex diseases across national borders. The ERN Experts (from one or more ERNs) will gather in multidisciplinary panels and use CPMS to carry out virtual consultations of rare and complex cases. There is one defined use case for each of the 6 Disease Groups within ERN-RND. Guest experts from centres that are not part of the ERN can also be invited to the panel.
The CPMS is not directly accessible to individual patients. However, with the patient’s consent and in accordance with the rules of their national health system, patient cases can be referred to the relevant ERN member in their country by their local clinician.

Panels are composed of experts with complementary expertise, which is essential for solving complex cases in the field of rare diseases and providing the best possible healthcare.

To find out more about the thinking behind the platform and how we expect it to work and be used, the European Commission has produced this short video.

Using the CPMS

In order to use the CPMS you have to have an EU login and subsequently register to CPMS.

Registration to CPMS
To register to CPMS, please follow the registration guide.

Login CPMS
To login into CPMS, please click here.

User guide
Please check the User guide to help you use the CPMS.

At a glance - 1 page documents
To join a panel directly please look here if you are a Panel Lead or a Panel Member.  To join a CPMS case discussion, please read the instructions here.

Technical requirements guide
For information on recommended browsers for CPMS best user experience, IP adresses to be whitelisted by hospitals, bandwith requirements, etc. please check the CPMS getting started guide for "hospitals".

Patient consents and data protection
Patients need to consent to the consultation of her/his case on CPMS.

The EU data protection officer has approved the CPMS. You can find the respective approval here.

CPMS training environment
If you would like to see how the system works and get familiarized with its individual features you can use the CPMS - training environment. There you can enrol a test-patient and go through all steps of a case discussion.
To access it, please go to:

To obtain the credentials of the CPMS training site, please contact the ERN-RND CPMS Helpdesk: sanja.hermanns[at]

Helpdesk and training
If you wish to receive a CPMS training session (live or online via zoom video-conference) and for any other kind of support, please contact the ERN-RND CPMS Helpdesk:

Sanja Hermanns, University Hospital Tübingen
Email: sanja.hermanns[at]

Péter Balicza, Semmelweis University Budapest
Email: baliczap[at]
Phone: +36-1-4591492

We roll out the CPMS use in ERN-RND use cases per disease group

Disease group Case summary
Ataxia/HSP Training of young neurologists and cohort formation
Leukodystrophies Diagnostically unclear and complex cases
Atypical Parkinsonian Syndromes Genetic PD Diagnostically unclear and complex cases
Dystonia/paroxysmal disorders/NBIA Unsolved cases after comprehensive genetic testing
Choreas and Huntington’s disease Patients with bona fide HD-like phenotypes but unknown aetiology
FTD To be determined